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Noise-rearing disrupts the maturation of multisensory integration.
- Source :
-
European Journal of Neuroscience . Feb2014, Vol. 39 Issue 4, p602-613. 12p. - Publication Year :
- 2014
-
Abstract
- It is commonly believed that the ability to integrate information from different senses develops according to associative learning principles as neurons acquire experience with co-active cross-modal inputs. However, previous studies have not distinguished between requirements for co-activation versus co-variation. To determine whether cross-modal co-activation is sufficient for this purpose in visual-auditory superior colliculus ( SC) neurons, animals were reared in constant omnidirectional noise. By masking most spatiotemporally discrete auditory experiences, the noise created a sensory landscape that decoupled stimulus co-activation and co-variance. Although a near-normal complement of visual-auditory SC neurons developed, the vast majority could not engage in multisensory integration, revealing that visual-auditory co-activation was insufficient for this purpose. That experience with co-varying stimuli is required for multisensory maturation is consistent with the role of the SC in detecting and locating biologically significant events, but it also seems likely that this is a general requirement for multisensory maturation throughout the brain. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0953816X
- Volume :
- 39
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- European Journal of Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 94447983
- Full Text :
- https://doi.org/10.1111/ejn.12423