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Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2.
- Source :
-
Biochemical & Biophysical Research Communications . Feb2014, Vol. 444 Issue 4, p555-561. 7p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] Dh404 suppresses the expression of a selected set of pro-inflammatory cytokines in inflamed macrophages via activating Nrf2. [•] Dh404 activates Nrf2 while keeping Keap1 function intact in macrophages. [•] Dh404 minimally regulates NF-κB pathway in macrophages. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 444
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 94639984
- Full Text :
- https://doi.org/10.1016/j.bbrc.2014.01.101