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MyD88 and IL-1: Loosening Treg cells’ firm grip.

Authors :
Campbell, Daniel J.
Source :
Trends in Immunology. Mar2014, Vol. 35 Issue 3, p95-96. 2p.
Publication Year :
2014

Abstract

Immune suppression by Treg cells must be overcome to mount robust and effective anti-pathogen immune responses. A new paper in Immunity from Medzhitov and colleagues shows that IL-1-dependent activation of MyD88 promotes the development of Th1 cells by rendering them impervious to Treg cell-mediated inhibition. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14714906
Volume :
35
Issue :
3
Database :
Academic Search Index
Journal :
Trends in Immunology
Publication Type :
Academic Journal
Accession number :
94688071
Full Text :
https://doi.org/10.1016/j.it.2014.02.001