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A Novel Inversion Technique for Imaging Thrombus Volume in Microchannels Fusing Optical and Impedance Data.
- Source :
-
IEEE Transactions on Magnetics . Feb2014, Vol. 50 Issue 2, p1021-1024. 4p. - Publication Year :
- 2014
-
Abstract
- The aim of this paper is to present a novel inversion technique to measure the volume of thrombus induced under blood flow conditions in a lab-on-a-chip device. The device is composed by a microscope slide where gold electrodes are sputtered and by a polydimethylsiloxane microchannel placed on the top of the slide. A thrombogenic substance is placed on the slide in such a way that hemostasis is induced when whole blood flows in the microchannel. The novel idea behind the inversion technique is to fuse optical and electrical impedance data to obtain a quasi-real-time reconstruction of thrombus volume. This is not possible with present state-of-the-art optical imaging based on confocal microscopy, which provides the thrombus volume estimation only at the end of the thrombus formation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00189464
- Volume :
- 50
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- IEEE Transactions on Magnetics
- Publication Type :
- Academic Journal
- Accession number :
- 94864096
- Full Text :
- https://doi.org/10.1109/TMAG.2013.2281987