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Synthesis and antifungal evaluation of imines derived from 3-Amino-2-isopropyl-3H-quinazolin-4-one.

Authors :
Karakaya, Idris
Karabuga, Semistan
Ulukanli, Zeynep
Ulukanli, Sabri
Source :
Organic Communications. 2013, Vol. 6 Issue 4, p139-147. 9p.
Publication Year :
2013

Abstract

Novel Schiff bases were synthesised using 3-aminoquinazolinone (1) and a variety of aldehydes in the presence of acetic acid as solvent. Antifungal evaluation of the compounds was carried out by the agar dilution method. Among the all compounds prepared, quinazolinone itself showed the best fungiostatic activity against all filamentous fungi. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13076175
Volume :
6
Issue :
4
Database :
Academic Search Index
Journal :
Organic Communications
Publication Type :
Academic Journal
Accession number :
94881130