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Immune regulatory activities of fowlicidin-1, a cathelicidin host defense peptide.

Authors :
Bommineni, Yugendar R.
Pham, Giang H.
Sunkara, Lakshmi T.
Achanta, Mallika
Zhang, Guolong
Source :
Molecular Immunology. May2014, Vol. 59 Issue 1, p55-63. 9p.
Publication Year :
2014

Abstract

Highlights: [•] Fowlicidin-1(6-26) is chemotactic to neutrophils without enhancing their oxidative burst activity. [•] Fowl-1(6-26) activates macrophages by inducing chemokine/cytokine expression. [•] Fowl-1(6-26) activates macrophages also by enhancing the surface expression of MHC II and CD86. [•] Fowl-1(6-26) protects mice if given 1–4 days prior to MRSA infection. [•] Fowl-1(6-26) augments ovalbumin-specific adaptive immune response. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
01615890
Volume :
59
Issue :
1
Database :
Academic Search Index
Journal :
Molecular Immunology
Publication Type :
Academic Journal
Accession number :
94896303
Full Text :
https://doi.org/10.1016/j.molimm.2014.01.004