Desarrollo de un atlas cerebral de resonancia magnética en T1: resultados preliminares.

Objectives: To present the preliminary results of the development of a brain Atlas based MRI of healthy Mexican subjects. Materials and Methods: A set of magnetic resonance images of 10 healthy subjects were selected to build an Atlas in accordance with the standards of the International Consortium for Brain Mapping. The software programs Brain Extraction Tool and Automatic Image Registration were used for preprocessing and automatic linear registration (and nonlinear) of MRI, respectively. The MRI were linear transformed to build an initial template for the construction of the Atlas. Subsequently, nonlinear transformations were applied using a polynomial of 5th order and then averaged. The resulting Atlas based on Mexican population was compared morphologically with Chinese (CHINESE_56) and Caucasian (ICBM152) populations. Results: The resulting Atlas meets the proposed ICBM methodology for developing of brain templates. The structural comparison between the Atlases shows differences between Mexican, Chinese and Caucasian populations. Conclusions: A Mexican Atlas was developed with a group of MRI of 10 healthy subjects. This Atlas is qualitatively comparable with CHINESE_56 and ICBM152 Atlas, although the results are not conclusive; they exhibit morphological differences between Mexican, Chinese and Caucasian populations. [ABSTRACT FROM AUTHOR]