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A (1-->4)-`trehazoloid' glucosidase inhibitor with aglycon selectivity.

Authors :
Knapp, Spencer
Purandare, Ashok
Source :
Journal of the American Chemical Society. 8/10/94, Vol. 116 Issue 16, p7461. 2p. 9 Diagrams.
Publication Year :
1994

Abstract

Describes the synthesis of the (1-->4)-linked `trehazoloid' analogous to trehazolin, an alpha,alpha-trehalase inhibitor. Synthesis of the trehazolin aminocyclitol portion; Competitive inhibition of yeast alpha-glucosidase by trehazoloid; Selectivity due to aglycon portion.

Details

Language :
English
ISSN :
00027863
Volume :
116
Issue :
16
Database :
Academic Search Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
9502220156
Full Text :
https://doi.org/10.1021/ja00095a081