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Molecular characterization of three loss-of-function mutations in the isopenicillin...

Authors :
Fernandez, Francisco J.
Gutierrez, Santiago
Source :
Journal of Bacteriology. Aug94, Vol. 176 Issue 16, p4941. 9p. 5 Black and White Photographs, 5 Diagrams, 1 Chart.
Publication Year :
1994

Abstract

Presents a molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum. Npe6; Npe7; Npe8; Comparison with npe10, a deletion mutant; Production of single amino acid changes in modified N-acyltransferases; Recovery of enzyme activity following construction of hybrid molecules.

Details

Language :
English
ISSN :
00219193
Volume :
176
Issue :
16
Database :
Academic Search Index
Journal :
Journal of Bacteriology
Publication Type :
Academic Journal
Accession number :
9503032686