Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval.

Presents the results of a genome-wide search in a four-generation pedigree with autosomal dominant early-onset dementia. Exclusion of the known Alzheimer's disease genes and mutations in the prion protein gene and exons 9-13 of the microtubule; Resemblance of the phenotype to frontotemporal dementia.