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A Semi-Pinacol Rearrangement Approach to Bicyclo[3.2.1]octan-2-ones and Bicyclo[3.2.1]octan-3-ones.

Authors :
Lee, Sejin
Kim, Keunho
Cha, Jin Kun
Source :
Synlett. 2008, Issue 14, p2155-2157. 3p.
Publication Year :
2008

Abstract

A diastereoselective approach to bicyclo[3.2.1]octan-2-ones and -3-ones is achieved by means of the semi-pinacol rearrangement of 2,3-epoxy silyl ethers. The key 1,2-migration is stereospecific. This method is easily amenable to an enantioselective synthesis by utilizing nonracemic norcamphor and related compounds. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09365214
Issue :
14
Database :
Academic Search Index
Journal :
Synlett
Publication Type :
Academic Journal
Accession number :
95202040
Full Text :
https://doi.org/10.1055/s-2008-1077902