SCREENING OF CYANOBACTERIA STRAINS FROM DELHI AND NCR FOR ANTI-BACTERIAL POTENTIAL.

Cyanobacteria or blue green algae have an extraordinary potential of producing secondary metabolites which can be an ultimate source of newer drugs for future. The purified strain Anabaena showed best photoautotrophic growth at 28°C with specific growth and generation time were 0.098 and 10.0 hr respectively. The better biomass production and antibacterial activity on 30th days of culture. 16 cyanobacterial strains collected from different sites of Delhi and NCR (National Capital Region, INDIA) identified as Microcystis, Anabaena, Oscillatoria, Nostoc, Phormidium sps were examined for antibacterial properties. The crude methanolic intracellular extracts of 8 strains showed activity against non-pathogenic Enterobacter aerogens and all 16 given potential against pathogenic Escherichia coli. In which purified Anabaena sps given maximum antibacterial activity against E. coli while Anabaena (Johad) and Microcystis (water tank) from Manesar (Gurgaon, India) against E. aerogens. The same strain from different origin has different antibacterial activity. This interpretation indicates the biosynthesis of bioactive molecules is niche and species specific. [ABSTRACT FROM AUTHOR]