Effect of different drying methods on the quality of Angelicae Sinensis Radix evaluated through simultaneously determining four types of major bioactive components by high performance liquid chromatography photodiode array detector and ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry.

Highlights: [•] An HPLC-PDA method for quantifying four types of components in DG was developed. [•] The identities of analytes in samples were further confirmed by UHPLC-QTOF-MS/MS. [•] The effect of five advanced drying methods on the holistic quality of DG was revealed. [•] Hot air-drying keeps the similar chemical composition of dried DG slices with that of fresh DG. [•] Vacuum-drying retains the highest contents of the major components in DG whole roots. [Copyright &y& Elsevier]