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Astrogliosis as a therapeutic target for neurodegenerative diseases.

Authors :
Colangelo, Anna Maria
Alberghina, Lilia
Papa, Michele
Source :
Neuroscience Letters. Apr2014, Vol. 565, p59-64. 6p.
Publication Year :
2014

Abstract

Highlights: [•] We briefly review the role of astrocytes in brain function. [•] We review the main pathways in astrocytic dysfunction. [•] We focus on astroglial-specific targets for clinical management of neurodegenerative disorders. [•] We describe the usefulness of a systems biology approach in drug discovery for neurodegenerative disorders. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
03043940
Volume :
565
Database :
Academic Search Index
Journal :
Neuroscience Letters
Publication Type :
Academic Journal
Accession number :
95225975
Full Text :
https://doi.org/10.1016/j.neulet.2014.01.014