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Adaptive hp finite element method for fluorescence molecular tomography with simplified spherical harmonics approximation.
- Source :
-
Journal of Innovative Optical Health Sciences . Apr2014, Vol. 7 Issue 2, p-1. 12p. - Publication Year :
- 2014
-
Abstract
- Recently, the simplified spherical harmonics equations (SPN) model has attracted much attention in modeling the light propagation in small tissue geometries at visible and near-infrared wavelengths. In this paper, we report an efficient numerical method for fluorescence molecular tomography (FMT) that combines the advantage of SPN model and adaptive hp finite element method (hp-FEM). For purposes of comparison, hp-FEM and h-FEM are, respectively applied to the reconstruction process with diffusion approximation and SPN model. Simulation experiments on a 3D digital mouse atlas and physical experiments on a phantom are designed to evaluate the reconstruction methods in terms of the location and the reconstructed fluorescent yield. The experimental results demonstrate that hp-FEM with SPN model, yield more accurate results than h-FEM with diffusion approximation model does. The phantom experiments show the potential and feasibility of the proposed approach in FMT applications. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17935458
- Volume :
- 7
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Innovative Optical Health Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 95466715
- Full Text :
- https://doi.org/10.1142/S1793545813500570