Metabolism: Targeting a fat-accumulation gene.

The article focuses on a enzyme that links two metabolic hubs in human body. It states that the enzyme has been found to be unregulated in the fat cells of overweight mice. It further states that the inhibition of the gene encoding this enzyme protects mice from diet-induced obesity. It further highlights that mice that lack or overexpress GLUT4 in fat are used as models for people sensitized to or resistant to diabetes.