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Tissue-, sex- and development-specific transcription profiles of eight UDP-glucuronosyltransferase genes in zebrafish (Danio rerio) and their regulation by activator of aryl hydrocarbon receptor.

Authors :
Christen, Verena
Fent, Karl
Source :
Aquatic Toxicology. May2014, Vol. 150, p93-102. 10p.
Publication Year :
2014

Abstract

Highlights: [•] Ugts are important phase II enzymes, of which little is known in fish. [•] Design of primers for RT-qPCR is challenging due to high sequence homologies. [•] We specify eight different Ugts in zebrafish. [•] We report tissue-, sex- and developmental specific transcription profiles. [•] Regulation of ugts by arylhydrocarbon receptor 2 is demonstrated. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0166445X
Volume :
150
Database :
Academic Search Index
Journal :
Aquatic Toxicology
Publication Type :
Academic Journal
Accession number :
95627420
Full Text :
https://doi.org/10.1016/j.aquatox.2014.02.019