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Higher LRRFIP1 expression in glioblastoma multiforme is associated with better response to teniposide, a type II topoisomerase inhibitor.
- Source :
-
Biochemical & Biophysical Research Communications . Apr2014, Vol. 446 Issue 4, p1261-1267. 7p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] The expression levels of LRRFIP1 are higher in VM-26 treated GBM patients with long five year survival rate. [•] LRRFIP1 chemosensitizes U373MG cells to VM-26 and inhibits U373MG cell progression. [•] LRRFIP1 suppresses GBM tumor growth in vivo. [•] LRRFIP1 reverses the effect of miR-21 in VM-26 resistant on GBM cells. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 446
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 95670741
- Full Text :
- https://doi.org/10.1016/j.bbrc.2014.03.105