Microfluidics-Based inVivo Mimetic Systems for theStudy of Cellular Biology.

The human body is a complex network of molecules,organelles, cells,tissues, and organs: an uncountable number of interactions and transformationsinterconnect all the system’s components. In addition to thesebiochemical components, biophysical components, such as pressure,flow, and morphology, and the location of all of these interactionsplay an important role in the human body. Technical difficulties havefrequently limited researchers from observing cellular biology asit occurs within the human body, but some state-of-the-art analyticaltechniques have revealed distinct cellular behaviors that occur onlyin the context of the interactions. These types of findings have inspiredbioanalytical chemists to provide new tools to better understand thesecellular behaviors and interactions. [ABSTRACT FROM AUTHOR]