ChemInform Abstract: Probing Binding and Cellular Activity of Pyrrolidinone and Piperidinone Small Molecules Targeting the Urokinase Receptor.

The synthesis of heterocyclic amides containing pyrrole, pyrrolidinone, and piperidone fragments is described and these are tested together with a wide range of previously prepared analogous derivatives for their binding activity at the urokinase receptor. [ABSTRACT FROM AUTHOR]