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Oncogenic osteomalacia illustrating the effect of fibroblast growth factor 23 on phosphate homeostasis.
- Source :
-
Clinical Kidney Journal . Jun2012, Vol. 5 Issue 3, p240-243. 4p. - Publication Year :
- 2012
-
Abstract
- In oncogenic osteomalacia (OOM), fibroblast growth factor 23 (FGF23) induces renal phosphate wasting and inhibits the appropriate increase of calcitriol. A patient suffering from OOM is described. Serum calcium, phosphate, biointact parathyroid hormone and intact FGF23 as well as the calcitriol and 24,25-vitamin D levels were measured before and after tumour removal. The clinical approach to a patient with hypophosphataemia is discussed and the changes in mineral metabolism after removal of a FGF23-producing tumour are described. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 20488505
- Volume :
- 5
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Clinical Kidney Journal
- Publication Type :
- Academic Journal
- Accession number :
- 95750416
- Full Text :
- https://doi.org/10.1093/ckj/sfs031