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Desymmetrization of Diolefinic Diols by Enantioselective Amino-thiocarbamate-Catalyzed Bromoetherification: Synthesis of Chiral Spirocycles.

Authors :
Tay, Daniel Weiliang
Leung, Gulice Y. C.
Yeung, Ying-Yeung
Source :
Angewandte Chemie. May2014, Vol. 126 Issue 20, p5261-5264. 4p.
Publication Year :
2014

Abstract

A facile, efficient, and highly diastereo- and enantioselective bromoetherification of diolefinic diols has been developed using an amino-thiocarbamate catalyst. Further manipulations of the bromoether products enabled entry into a new class of spirocycles which are distinctively lacking in the literature. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00448249
Volume :
126
Issue :
20
Database :
Academic Search Index
Journal :
Angewandte Chemie
Publication Type :
Academic Journal
Accession number :
95909024
Full Text :
https://doi.org/10.1002/ange.201310136