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5-fluoro glycosides: A new class of mechanism-based inhibitors of both alpha- and beta-glucosidases.

Authors :
McCarter, John D.
Withers, Stephen G.
Source :
Journal of the American Chemical Society. 1/10/96, Vol. 118 Issue 1, p241. 2p. 1 Graph.
Publication Year :
1996

Abstract

Focuses on 5-fluro glycosides, a new class of mechanism-based inhibitors of both alpha- and beta-glucosidases. Role of glycosidase inhibitors as probes of enzymic mechanism; Design of inhibitors; Synthesis of the 5-fluoroglycosyl fluorides.

Subjects

Subjects :
*GLUCOSIDASE inhibitors
*BIOSYNTHESIS

Details

Language :
English
ISSN :
00027863
Volume :
118
Issue :
1
Database :
Academic Search Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
9601314750
Full Text :
https://doi.org/10.1021/ja952732a
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