Copper powder-catalyzed N-arylation of imidazoles in water using 2-(hydrazinecarbonyl)pyridine N-oxides as the new ligands.

Authors :: Wu, Feng-Tian
Yan, Nan-Nan
Liu, Ping
Xie, Jian-Wei
Liu, Yan
Dai, Bin
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. May2014, Vol. 55 Issue 21, p3249-3251. 3p.
Publication Year :: 2014
Abstract: Abstract: 2-(2-Hydrazinecarbonyl)pyridine N-oxides, which were derived from pyrrole-2-carbohydrazides and pyridine N-oxides, were synthesized and utilized as the ligands for copper powder-catalyzed N-arylation of imidazoles with aryl halides in water. Imidazoles could be arylated smoothly with various aryl halides to provide the title products in preferable yields without the need of an inert atmosphere. [Copyright &y& Elsevier]

Subjects :: *COPPER powder
*COPPER catalysts
*ARYLATION
*IMIDAZOLES
*WATER analysis
*PYRIDINE oxide
*LIGANDS (Chemistry)
*ARYL halides

Language :: English
ISSN :: 00404039
Volume :: 55
Issue :: 21
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 96020726
Full Text :: https://doi.org/10.1016/j.tetlet.2014.04.039

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