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A novel conformation in a highly potent, constrained gonadotropin-releasing hormone antagonist.

Authors :
Rizo, Josep
Sutton, R. Byran
Source :
Journal of the American Chemical Society. 2/7/96, Vol. 118 Issue 5, p970. 7p. 7 Diagrams, 5 Charts.
Publication Year :
1996

Abstract

Studies the structural requirements for biological activity through the design, synthesis of constrained gonadotropin releasing hormone. Nuclear magnetic resonance studies; Computational analysis.

Details

Language :
English
ISSN :
00027863
Volume :
118
Issue :
5
Database :
Academic Search Index
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
9602283086
Full Text :
https://doi.org/10.1021/ja953207e