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The immunological evolution of catalysis.
- Source :
-
Science . 2/23/1996, Vol. 271 Issue 5252, p1086. 5p. 4 Color Photographs, 2 Diagrams, 1 Chart, 4 Graphs. - Publication Year :
- 1996
-
Abstract
- Reports on a study that cloned and expressed nine affinity mutations form germline cells that occurred during the generation of an antibody that catalyzes ester hydrolysis. Findings from the kinetic analysis; Indications that the mutations were not in direct contact with the hapten of the antibody and played a conformational role.
- Subjects :
- *IMMUNOGLOBULINS
*GENETIC mutation
Subjects
Details
- Language :
- English
- ISSN :
- 00368075
- Volume :
- 271
- Issue :
- 5252
- Database :
- Academic Search Index
- Journal :
- Science
- Publication Type :
- Academic Journal
- Accession number :
- 9603144672
- Full Text :
- https://doi.org/10.1126/science.271.5252.1086