Bleomycin sulphate loaded nanostructured lipid particles augment oral bioavailability, cytotoxicity and apoptosis in cervical cancer cells.

Highlights: [•] Nanostructure lipid particles of bleomycin sulphate enhanced the oral bioavailability by averting first pass metabolism. [•] Nanostructure lipid particles augmented intestinal lymphatic uptake of bleomycin sulphate to reach the systemic circulation. [•] The nanoformulation of bleomycin sulphate improved the cytotoxicity and extent of apoptosis against cervical cancer cells. [ABSTRACT FROM AUTHOR]