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Aquaporin-11 control of testicular fertility markers in Syrian hamsters.

Authors :
Shannonhouse, John L.
Urbanski, Henryk F.
Woo, Shih-Lung
Fong, Li An
Goddard, Scott D.
Lucas, William F.
Jones, Edward R.
Wu, Chaodong
Morgan, Caurnel
Source :
Molecular & Cellular Endocrinology. Jun2014, Vol. 391 Issue 1/2, p1-9. 9p.
Publication Year :
2014

Abstract

Highlights: [•] Differential display PCR revealed candidate genes for control of fertility in testis during photoperiodic modulation. [•] Multiple linear regression modeling helped identify aquaporin-11 as the best fit among the candidate genes. [•] RNA interference of Aqp11, using small interfering RNA demonstrated Aqp11 tonically induces markers of fertility. [•] The collective results provide the first molecular evidence that Aqp11 regulates fertility. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03037207
Volume :
391
Issue :
1/2
Database :
Academic Search Index
Journal :
Molecular & Cellular Endocrinology
Publication Type :
Academic Journal
Accession number :
96233307
Full Text :
https://doi.org/10.1016/j.mce.2014.04.011