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Role of astrocytes in the neuroprotective actions of 17β-estradiol and selective estrogen receptor modulators.

Authors :
Acaz-Fonseca, Estefania
Sanchez-Gonzalez, Rebeca
Azcoitia, Iñigo
Arevalo, Maria Angeles
Garcia-Segura, Luis M.
Source :
Molecular & Cellular Endocrinology. May2014, Vol. 389 Issue 1/2, p48-57. 10p.
Publication Year :
2014

Abstract

Highlights: [•] Estradiol regulates reactive astrogliosis and the inflammatory response of astrocytes. [•] Estradiol regulates neuroglobin expression in astrocytes. [•] Estradiol regulates the synthesis of neurotrophic factors in astrocytes. [•] Estradiol controls edema by regulating aquaporin 4 expression in astrocytes. [•] Estradiol controls excitotoxicity by regulating glutamate transport by astrocytes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03037207
Volume :
389
Issue :
1/2
Database :
Academic Search Index
Journal :
Molecular & Cellular Endocrinology
Publication Type :
Academic Journal
Accession number :
96233321
Full Text :
https://doi.org/10.1016/j.mce.2014.01.009