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Human intestinal spirochetosis is significantly associated with sessile serrated adenomas/polyps.
- Source :
-
Pathology - Research & Practice . Jul2014, Vol. 210 Issue 7, p440-443. 4p. - Publication Year :
- 2014
-
Abstract
- Abstract: It remains unclear whether or not human intestinal spirochetosis (HIS) has any associated symptoms or lesions. In this study, we assessed the prevalence of HIS in sessile serrated adenomas/polyps (SSA/Ps) and their possible association. Following identification of early cecal cancer with SSA/P accompanied by a colonization of HIS, we went on to conduct a retrospective case-control study using endoscopically resected SSA/P specimens to examine the frequency of HIS infection in SSA/Ps. Nineteen SSA/P cases and 172 controls were obtained. The rate of HIS infection was significantly higher at 52.6% (10/19) in the SSA/P cases compared to the controls at 8.1% (14/172). Our SSA/P series were associated with a remarkably higher rate of HIS than controls or than previously reported. This is the first report to provide evidence for potential association between HIS and SSA/Ps. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 03440338
- Volume :
- 210
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Pathology - Research & Practice
- Publication Type :
- Academic Journal
- Accession number :
- 96233456
- Full Text :
- https://doi.org/10.1016/j.prp.2014.03.007