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Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons.
- Source :
-
Gene Expression Patterns . May2014, Vol. 15 Issue 1, p31-37. 7p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] A comparative analysis of the spatiotemporal expression of POU4F1, POU4F2, and ISL1 during mouse inner ear neurogenesis. [•] ISL1 expression starts in the otic epithelium and precedes POU4F1 expression in cochleovestibular ganglion (CVG) neurons. [•] POU4F1 is co-expressed with ISL1 and NEUROD1 in delaminated CVG neurons. [•] POU4F2 expression starts after that of POU4F1 and ISL1, and is expressed in post-mitotic, NEUROD1-negative CVG neurons. [•] The temporal expression order of these transcription factors in mouse CVG neurogenesis is NEUROD1>ISL1>POU4F1>POU4F2. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 1567133X
- Volume :
- 15
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Gene Expression Patterns
- Publication Type :
- Academic Journal
- Accession number :
- 96343149
- Full Text :
- https://doi.org/10.1016/j.gep.2014.03.001