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MicroRNA-106b in cancer-associated fibroblasts from gastric cancer promotes cell migration and invasion by targeting PTEN.

Authors :
Yang, Ting-Song
Yang, Xiao-Hu
Chen, Xi
Wang, Xu-Dong
Hua, Jie
Zhou, Dong-Lei
Zhou, Bo
Song, Zhen-Shun
Source :
FEBS Letters. Jun2014, Vol. 588 Issue 13, p2162-2169. 8p.
Publication Year :
2014

Abstract

Highlights: [•] MiR-106b is up-regulated in CAFs compared to NFs in gastric cancer. [•] Down-regulation of miR-106b in CAFs inhibits cancer cell motility by targeting PTEN. [•] MiR-106b might be a potential therapeutic target for gastric cancer. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00145793
Volume :
588
Issue :
13
Database :
Academic Search Index
Journal :
FEBS Letters
Publication Type :
Academic Journal
Accession number :
96343355
Full Text :
https://doi.org/10.1016/j.febslet.2014.04.050