Back to Search
Start Over
1,2- N-Migration in a Gold-Catalysed Synthesis of Functionalised Indenes by the 1,1-Carboalkoxylation of Ynamides.
- Source :
-
Chemistry - A European Journal . Jun2014, Vol. 20 Issue 24, p7262-7266. 5p. - Publication Year :
- 2014
-
Abstract
- Unique α-hemiaminal ether gold carbene intermediates were accessed by a gold-catalysed 1,1-carboalkoxylation strategy and evolved through a highly selective 1,2- N-migration. This skeletal rearrangement gave functionalised indenes, and isotopic labelling confirmed the rare CN bond cleavage of the ynamide moiety. The effect of substituents on the migration has been explored, and a model is proposed to rationalise the observed selectivity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *INDENE synthesis
*ALKOXYLATION
*YNAMIDES
*ISOTOPIC analysis
*FUNCTIONAL analysis
Subjects
Details
- Language :
- English
- ISSN :
- 09476539
- Volume :
- 20
- Issue :
- 24
- Database :
- Academic Search Index
- Journal :
- Chemistry - A European Journal
- Publication Type :
- Academic Journal
- Accession number :
- 96364112
- Full Text :
- https://doi.org/10.1002/chem.201403040