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Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population.

Authors :
Gulati, Sachin
Yadav, Anita
Kumar, Neeraj
Kanupriya
Kumar, Gaurav
Aggarwal, Neeraj
Gupta, Ranjan
Source :
Environmental Toxicology & Pharmacology. May2014, Vol. 37 Issue 3, p1186-1193. 8p.
Publication Year :
2014

Abstract

Highlights: [•] The genotype frequency of CYP2C19*2, *3, 2E1*5B, 3A4*1B were found to be 22.0%, 0.0%, 2.11% and 2.0% respectively. [•] We found no significant distribution of CYP genotypes among males and females. [•] The study of XMG may provide opportunities for screening and getting reduction in environment risk factor. [•] The study would be helpful for pharmacogenic testing in Haryana population. [•] The study would be helpful for drug induced toxicity and therapeutic failures. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
13826689
Volume :
37
Issue :
3
Database :
Academic Search Index
Journal :
Environmental Toxicology & Pharmacology
Publication Type :
Academic Journal
Accession number :
96438357
Full Text :
https://doi.org/10.1016/j.etap.2014.03.013