A versatile and efficient synthesis of (2S)-2-(hydroxymethyl)-N-Boc-2,3-dihydro-4-pyridone

Authors :: Shashidhar Kumar, A.
Haritha, B.
Venkateswara Rao, B.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. May2003, Vol. 44 Issue 22, p4261. 3p.
Publication Year :: 2003
Abstract: A versatile and efficient method for the preparation of (2S)-2-(hydroxymethyl)-N-Boc-2,3-dihydro-4-pyridone from l-(−)-phenylalanine 2 utilising the aromatic system as a masked β-keto aldehyde was developed. The key step in the sequence is an intramolecular cyclisation of 6 to give 2,3-dihydropyridin-4-ones. [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 44
Issue :: 22
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 9655200
Full Text :: https://doi.org/10.1016/S0040-4039(03)00888-8

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