Chiral Co(II) complex catalyzed asymmetric Michael reactions of β-ketoamides to nitroolefins and alkynones.

Authors :: Zhang, Zuliang
Liu, Xiaohua
Wang, Zhen
Zhao, Xiaohu
Lin, Lili
Feng, Xiaoming
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2014, Vol. 55 Issue 28, p3797-3801. 5p.
Publication Year :: 2014
Abstract: Abstract: The catalytic enantioselective Michael additions of cyclic β-ketoamides to nitroolefins and alkynones were accomplished in the presence of chiral N,N′-dioxide–Co(II) complexes. The desired adducts were obtained in high yields (up to 98%) with excellent enantioselectivities (up to 97%ee). [Copyright &y& Elsevier]

Subjects :: *COBALT
*ENANTIOSELECTIVE catalysis
*MICHAEL reaction
*AMIDES
*NITROALKENES
*COMPLEX compounds

Language :: English
ISSN :: 00404039
Volume :: 55
Issue :: 28
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 96660048
Full Text :: https://doi.org/10.1016/j.tetlet.2014.05.067

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