Modulation of the transcriptional response of innate immune and RNAi genes upon exposure to dsRNA and LPS in silkmoth-derived Bm5 cells overexpressing BmToll9-1 receptor.

Highlights: [•] Generation of Bm5 transformed cell line that expresses BmToll9-1. [•] Higher transcriptional response of Dcr2 by dsRNA in BmToll9-1 expressing cells. [•] Lower transcriptional response of innate immune pathway and AMP genes to LPS in BmToll9-1 expressing cells. [•] No direct modulation of RNAi process by BmToll9-1. [ABSTRACT FROM AUTHOR]