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Copper-Catalyzed [18F]Fluorination of (Mesityl)(aryl)iodoniumSalts.
- Source :
-
Organic Letters . Jun2014, Vol. 16 Issue 12, p3224-3227. 4p. - Publication Year :
- 2014
-
Abstract
- A practical, rapid, and highly regioselectiveCu-catalyzed radiofluorinationof (mesityl)(aryl)iodonium salts is described. This protocol utilizes[18F]KF to access 18F-labeled electron-rich,-neutral, and -deficient aryl fluorides under a single set of mildconditions. This methodology is applied to the synthesis of protectedversions of two important radiotracers: 4-[18F]fluorophenylalanineand 6-[18F]fluoroDOPA. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 16
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 96839989
- Full Text :
- https://doi.org/10.1021/ol501243g