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Syntheses, Characterizations, Crystal structures, and Antitumor Activities of Arenetelluronic Triorganotin Esters.
- Source :
-
Heteroatom Chemistry . Jul2014, Vol. 25 Issue 4, p217-225. 9p. - Publication Year :
- 2014
-
Abstract
- ABSTRACT Six new arenetelluronic triorganotin esters, namely (R3Sn)4[ArTe(μ-O)(OH)O2)]2 (Ar = Ph, R = Me: 1, R = Ph: 2; Ar = 3-Me-Ph, R = Me: 3, R = Ph: 4, Ar = 3-Cl-Ph, R = Me: 5, R = Ph: 6), were prepared by treating arenetelluronic acids with the corresponding R3SnCl (R = Me, Ph) with potassium hydroxide in methanol. All complexes were characterized by elemental analysis, FT-IR, NMR (1H, 13C, 119Sn) spectroscopy, and X-ray crystallography. The structural analyses indicate that these complexes are isostructural as Sn4Te2 moiety, in which the Te2(μ2-O)2 units are situated in the center and each Te atom is coordinated with two OSnR3 groups on the side. Complexes 1, 3, and 5 show one-dimensional chain and two-dimensional network supramolecular structures by intermolecular CH···O or CH···Cl interactions. The antitumor activities of these complexes reveal that most arenetelluronic triorganotin esters have powerful antitumor activities with certain regularity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *POTASSIUM hydroxide
*METHANOL
*X-ray crystallography
*ANTINEOPLASTIC agents
*ESTERS
Subjects
Details
- Language :
- English
- ISSN :
- 10427163
- Volume :
- 25
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Heteroatom Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 96986631
- Full Text :
- https://doi.org/10.1002/hc.21150