A novel mechanism of action of tetracyclines: Effects on nitric oxide synthases.

Authors :: Amin, Ashok R.
Attur, Mukundan G.
Source :: Proceedings of the National Academy of Sciences of the United States of America. 11/26/96, Vol. 93 Issue 24, p14014. 6p. 1 Color Photograph, 2 Diagrams, 2 Graphs.
Publication Year :: 1996
Abstract: Evaluates the effect of tetracyclines on the expression and function of human osteoarthritis (OA)-affected nitric oxide synthase (OA-NOS) and rodent inducible NOS. Cell lines and reagents; Effect of doxycycline and minocycline on inducible OA-NOS activity in human OA-affected cartilage; Effects of doxycycline and minocycline on iNOS in murine macrophages.

Language :: English
ISSN :: 00278424
Volume :: 93
Issue :: 24
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 9705162093
Full Text :: https://doi.org/10.1073/pnas.93.24.14014

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