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Inhibition of HIV infection of H9 cells by chlorpromazine derivatives.

Authors :
Weaver, James L.
Lee, Sherwin
Source :
Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. May97, Vol. 15 Issue 1, p16. 5p. 3 Black and White Photographs, 1 Chart, 2 Graphs.
Publication Year :
1997

Abstract

States that the binding between the human immunodeficiency virus (HIV) surface protein, gp120, and the CD4 coreceptor is known to be initiated by electrostatic interactions. Ability of chlorpromazine to interact with proteins by charge transfer; Results of the testing of several derivatives for their ability to block binding of HIV to CD4... cells.

Details

Language :
English
ISSN :
10779450
Volume :
15
Issue :
1
Database :
Academic Search Index
Journal :
Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology
Publication Type :
Academic Journal
Accession number :
9708245934