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Formation of scalemic aziridines via the nucleophilic opening of aziridines.

Authors :
Bergmeier, Stephen C.
Seth, Punit P.
Source :
Journal of Organic Chemistry. 04/18/97, Vol. 62 Issue 8, p2671. 4p. 6 Diagrams.
Publication Year :
1997

Abstract

Examines the formation of the scalemic aziridine molecules via the nucleophilic opening of aziridines. Protection of the free hydroxyl as a tert-butyldimethylsilyl ether; Formation of the arizidine ring via a Mitsunobu reaction; Preparation of the aziridine with an R configuration by an alternate route.

Subjects

Subjects :
*NUCLEOPHILIC reactions

Details

Language :
English
ISSN :
00223263
Volume :
62
Issue :
8
Database :
Academic Search Index
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
9711154531
Full Text :
https://doi.org/10.1021/jo962307f