The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport.

Authors :: Waterman-Storer, Clare M.
Karki, Sher B.
Source :: Proceedings of the National Academy of Sciences of the United States of America. 10/28/97, Vol. 94 Issue 22, p12180. 6p. 5 Black and White Photographs, 1 Chart.
Publication Year :: 1997
Abstract: Examines the effects of anti-dynactin antibodies on organelle transport in extruded axoplasm, to determine whether the heteromultimeric protein complex, dynactin, is required for retrograde axonal transport. What treatment of axoplasm with antibodies to the p150...subunit of dynactin resulted in; Investigation of the molecular mechanism of the observed inhibition of motility; What the results indicate.

Language :: English
ISSN :: 00278424
Volume :: 94
Issue :: 22
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 9711160232
Full Text :: https://doi.org/10.1073/pnas.94.22.12180

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