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Unlocking epigenetic codes in neurogenesis.
- Source :
-
Genes & Development . 6/15/2014, Vol. 28 Issue 12, p9-9. 1p. - Publication Year :
- 2014
-
Abstract
- During embryonic and adult neurogenesis, neuronal stem cells follow a highly conserved path of differentiation to give rise to functional neurons at various developmental stages. Epigenetic regulation--including DNA modifications, histone modifications, and noncoding regulatory RNAs, such as microRNA (miRNA) and long noncoding RNA (lncRNA)--plays a pivotal role in embryonic and adult neurogenesis. Here we review the latest in our understanding of the epigenetic regulation in neurogenesis, with a particular focus on newly identified cytosine modifications and their dynamics, along with our perspective for future studies. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DEVELOPMENTAL neurobiology
*DNA
*CYTOSINE
Subjects
Details
- Language :
- English
- ISSN :
- 08909369
- Volume :
- 28
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Genes & Development
- Publication Type :
- Academic Journal
- Accession number :
- 97280387
- Full Text :
- https://doi.org/10.1101/gad.241547.114