MicroRNA and Cervical Cancer.

MicroRNA (miRNA), a class of endogenous small non-coding regulatory RNAs, regulate the expression of target genes by pairing with its 3' untranslated regions (3'UTR) to induce the inhibited translation or mRNA degression. Mature miRNA may interfere with multiple biological processes involved in tumorigenesis such as cell proliferation, cell cycle, apoptosis, angiogenesis, invasion and metastasis. Multiple studies showed that the aberrant expression of miRNA, as novel potential makers, could provide numerous promising merits in diagnostic, pathological and therapeutic targets in cervical cancer. [ABSTRACT FROM AUTHOR]