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Detection of the novel IMP-38 among carbapenemase-producing Enterobacteriaceae in a university hospital, China.
- Source :
-
Journal of Infection in Developing Countries . Aug2014, Vol. 8 Issue 8, p1044-1048. 5p. - Publication Year :
- 2014
-
Abstract
- Introduction: This study set out to investigate the molecular epidemiology of carbapenemase-producing Enterobacteriaceae isolates collected from Xiang Ya Hospital, Hunan, China. Methodology: The carbapenemase genes from Enterobacteriaceae isolates were determined by PCR and sequencing. Relatedness of Klebsiella pneumoniae isolates was evaluated by pulsed-field gel electrophoresis. Results: Twenty-four out of 738 non-repetitive Enterobacteriaceae isolates harbored carbapenemase genes including IMP-38, a novel IMP- type metallo-enzyme. Nine IMP-38-producing isolates were shown to originate from the same clone and caused a small outbreak in the neonatal ward. Conclusions: IMP-38, a novel IMP-type metallo-enzyme, was one of the predominant types of carbapenemase in the clinical carbapenem-resistant Enterobacteriaceae isolates in our hospital. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20366590
- Volume :
- 8
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Journal of Infection in Developing Countries
- Publication Type :
- Academic Journal
- Accession number :
- 97480890
- Full Text :
- https://doi.org/10.3855/jidc.4179