An Efficient Synthesis of Isoxazoles and Pyrazoles under Ultrasound Irradiation.

A series of 5-arylisoxazole and 5-aryl-1 H-pyrazole derivatives was synthesized by the reaction of 3-(dimethylamino)-1-arylprop-2-en-1-one with hydroxylamine hydrochloride or hydrazine hydrate under ultrasound irradiation without using any catalyst. This method has the advantages of easier work-up, mild reaction condition, high yields, shorter reaction time, and environmentally benign procedure. [ABSTRACT FROM AUTHOR]