A Highly Concise and Convergent Synthesis of HCV PolymeraseInhibitor Deleobuvir (BI 207127): Application of a One-Pot Borylation–SuzukiCoupling Reaction.

A highlyconcise and convergent synthesis of HCV polymerase inhibitorDeleobuvir (BI 207127, 1) was achieved, featuring efficientPd-catalyzed one-pot borylation–Suzuki coupling where TFP wasidentified as the unique ligand effective for these transformations. [ABSTRACT FROM AUTHOR]