Cobalt-Catalyzed, Aminoquinoline-Directed Couplingof sp2C–H Bonds with Alkenes.

A methodfor cobalt-catalyzed, aminoquinoline-directed ortho-functionalization of sp2C–H bondswith alkenes has been developed. Reactions proceed at room temperaturein trifluoroethanol solvent, use oxygen from air as an oxidant, andrequire Mn(OAc)3as a cocatalyst. Benzoic, heteroaromatic,and acrylic acid aminoquinoline amides react with ethylene as wellas mono- and disubstituted alkenes affording products in good yields.Excellent functional group tolerance is observed; halogen, nitro,ether, and unprotected alcohol functionalities are compatible withthe reaction conditions. [ABSTRACT FROM AUTHOR]