Mesoporous Nanoparticles: Gated Mesoporous SiO2 Nanoparticles Using K+-Stabilized G-Quadruplexes (Adv. Funct. Mater. 36/2014).

On page 5662, I. Willner and team show how K+‐ion‐stabilized G‐quadruplexes act as locks for the entrapment of substrates in mesoporous silica nanoparticles. The pores are unlocked by the Kryptofi × [2.2.2] (KP) through the removal of the K+ ions. Also, programmed duplex structures lock the anticancer drug doxorubicin in mesoporous silica nanoparticles. The pores are unlocked by the separation of the duplex through the formation of a G‐quadruplex. [ABSTRACT FROM AUTHOR]